The eye and systemic health

Exploring what ophthalmic imaging can reveal about health elsewhere in the body

The eye permits direct, non-invasive visualisation of neural and vascular tissue. Changes visible in ophthalmic images may therefore reflect biological processes occurring elsewhere in the body.

I study these relationships by combining ophthalmic imaging with genetic, clinical, and multi-omic data. This work explores what the eye can tell us about cardiovascular and neurological health, while examining whether observed associations are biologically meaningful, clinically useful, and robust across different populations(Julian et al., 2026; Maldonado-Garcia et al., 2025).

Oculomics investigates relationships between features of the eye and health elsewhere in the body.

References

2026

  1. Journal article
    Multi-omic analysis of deep learning-derived phenotypes links ophthalmic imaging to cardiovascular and neurological traits
    Thomas H Julian, Haoran Dou, Jinming Duan, and 15 more authors
    Nature Cardiovascular Research, 2026

2025

  1. Journal article
    Predicting cardiovascular disease risk using retinal optical coherence tomography imaging
    Cynthia Maldonado-Garcia, Rodrigo Bonazzola, Enzo Ferrante, and 4 more authors
    Frontiers in Artificial Intelligence, 2025